lunesta and drug interactions. Drug labeling on this Web site is the most recent submitted to the Food and Drug Administration (FDA) and currently . Avoid drinking alcohol while taking Lunesta. Overview: Photos: How To Use: Side Effects: Precautions: Missed Dose: Drug Interactions: LUNESTA Uses This medication is used to treat sleep problems (insomnia). Everything you need to know about are there drug interactions between lunesta and diphenydramine?, including common uses, side effects, inter... more