Can acyclovir cause bladder infectiondisorders that cause pain with urination include bladder infection . of urinary crystals (sulfonamides and acyclovir). . . . Such an infection can be confirmed by a positive . . bladder and the urethra, through which urine is expelled out . you urinate as the urine that is left in your bladder causes further infections. . However application of a acyclovir ointment to . . . . Acyclovir 400 mg orally three times a day for 7 . . . . . usually treated with ant... more