Klonopin worksseems to be helping. 25mg twice a day. . . 5mg and i still feel nothingIve been on Klonopin for 9 months at 2mg and I feel no effect at all from it anymore. How does Klonopin work? When administered to humans, a single oral dose of Klonopin can give maximum blood levels of drug, in most cases, within one to two hours. Im basically taking it to avoid withdrawl. All the other PTSD patients I saw taking Klonopin (and Seroquel) were zombies! It's a nice work day for the mental health... more