Amoxicillin with liquorI'm taking Amoxicillin for a throat infection. . Best Answer: Alcohol activates an enzyme system in your liver called cytochrome P450. . . My recent break from the . htm . . Does drinking beer while taking Amoxicillin cancel out or interrupt the effects of the antibiotics? ChaCha Answer: There are no known. it can cause the medicine to not work as effectively and you . A friend of mine told me not to drink while I'm taking it because it will make them ineffective. There ... more