Vicodin downside. There has been a tendency to use stronger opioids such as hydrocodone (Vicodin . . . . . . . However, when abused, Vicodin can be dangerous. . . . Medical Marijuana's Downside. "But it has the same downside in that at the end of day you have no idea how much is . Suboxone detox; Tramadol detox; Ultram detox; Vicodin detox; Xodol detox; Zydone detoxThe downside is that they can cause physical and psychological dependence and . The downside is that they can cause physical and p... more