Ciprofloxacin hives. . . In clinical trials, oral ciprofloxacin was most . Your friend's symptoms (hives, rash, and swelling of the hands) are consistent with a condition called Serum . Signs of an allergic reaction are skin rash, hives and swelling. . Rare allergic reactions have been described, such as hives and anaphylaxis (shock). . . . Does anyone have a cure for hives reaction to ciprofloxacin ? Have had hives head to toe going on two weeks after completing cipro meds. Dewey, AZ: Cheryl ... more