How to take azithromycin 250 mgIf you take an . . . Consumer information about the medication AZITHROMYCIN 250/500 MG - ORAL (Zithromax . However, if you did take . . You can take them at the same time. . . . Best Answer: Take two tablets on the first day. Do not take an antacid at the same time as . Antacids can stop azithromycin from working. . This eMedTV page explains that the suggested dosage of azithromycin for treating most bacterial infections is 250 mg or 500 mg daily for three to fiv... more