Lexapro making me tired. i think it’s making . . . My doctor was saying it wouldn't make me gain weight . Send me the monthly Answers. . . I felt more able to talk . . . . Somebody out there talk to me. . . . . . . . Best Answer: i think so, i used to take it and i was really tired but its didnt help my depression much so the doc took me off it . Posted by: jessica santiago at September 1, 2006 6:43 PMBest Answer: Most SSRI's (like Cipralex) will make you drowsy. . . . . He have me Lexapr... more