Vyvanse and ritalin mix. What causes a problem is if I start adding caffeine to this mix. . We have now added 30mg of Vyvanse to the mix. . Answer I wouldn't recommend it, I would imagine the effect would be similar to someone drinking a lot of caffine while on speed. . Thread profile page for "Is it safe to mix ritalin with suboxone????? - Topix" on . No, please take my advice and not do this , it is very dangerous, and can seriously injure or kill you. Celexa is not on the list of medication... more