Ativan propofol midazolam. . . . 25-1 . . Jackson's death. agents should be used such as Propofol (Diprivan) or Midazolam (Versed). However, for long-term sedation, lorazepam is preferred due to its long duration of action, and propofol has advantages over midazolam when used in the ICU for sedation . . . . g. For longer periods of mechanical ventilation, longer acting agents such as Lorazepam (Ativan . . . . . . . Carrasco G, Molina R, Costa J, et al. phase 2 study, the Philips Bispectral D R... more