Fluoxetine dosage for dogs. In this study, dogs administered a 1 mg/kg dose of fluoxetine had plasma fluoxetine concentrations that continued to increase over the one-year dosing period. The maximum fluoxetine dose should not exceed 80 mg/day. 5 to 1 mg per pound (1 to 2 mg/kg) given every 24 hours, orally. For cats, the dose is 2 to 5 mg per cat once daily. Pediatric (children and . . He does designy things and funny things. 1800PetMeds offers Fluoxetine, an anxiety medication for dogs & ... more