Will zithromax treat strep throat. . Zithromax is a macrolide . . . . . . What conditions does Zithromax Z-Pak Oral treat? Zithromax Z-Pak Oral is used to treat the following: Strep Throat, Strep Throat and Tonsillitis, Acute Gonorrhea of the . an alternative to medications in the penicillin family. What is Zithromax? Return to top. . . . In children, it is used to treat middle ear infection, pneumonia, tonsillitis, and strep throat. . . . . Strep Throat; Trachoma; Travel Medicine; Complete . ... more