Can prilosec be taken in the evening. . . . . . "They can change the bacteria that live in . dosage of Prilosec, like twice in the morning and twice in the evening. . so one can use BOTH types of meds huh? And there are advantages to that? Right now I'm only taking Prilosec. Omeprazole (Prilosec ®) is a prescription medication used . . . Includes patient rankings on scale of 1-5, comments, side effects, dosage, sex, age, time taken. . . . If it is due to GERD Prilosec (PPI) even once a day ta... more