Seroquel and antihistamines. . . . Used to treat psychosis, schizophrenia, and acute manic episodes associated with bipolar . . . How to use Seroquel Oral. . In reply to does seroquel make you depressed?, posted by lexman on August 19, 2004, at 18:17:59. . . Read the Medication Guide and, if available, the Patient . Results for the following 2 drugs: Abilify (aripiprazole) Seroquel (quetiapine) . Seroquel & Zyprexa are very potent antihistamines which is why they are . . Used to prevent mo... more